2022 Girls Varsity Softball
Season:
| Thu, Mar 17 | Scrimmages (A) vs Mercy McAuley | 7-2 | St. James Athletic Field |
| Sat, Mar 19 | Scrimmages (A) vs Milford | 11:00 AM | Milford High School |
| Wed, Mar 23 | Scrimmages (A) vs West Clermont | 5-9 | West Clermont High School |
| Thu, Mar 24 | Home vs Anderson | 5:00 PM | William Henry Harrison High School |
| Sat, Mar 26 | Home vs Turpin | 11:00 AM | William Henry Harrison High School |
| Sat, Mar 26 | Home vs Ursuline Academy | 12:30 PM | William Henry Harrison High School |
| Sat, Mar 26 | Home vs Ursuline Academy | 2:00 PM | William Henry Harrison High School |
| Mon, Mar 28 | Home vs South Dearborn | W 7-6 | 1-0 |
| Tue, Mar 29 | Home vs Mt. Notre Dame | L 6-9 | 1-1 |
| Thu, Mar 31 | Away vs Hamilton | W 21-2 | 2-1 |
| Fri, Apr 01 | Home vs Seton | W 7-4 | 3-1 |
| Mon, Apr 04 | Away vs Edgewood | W 20-4 | 4-1 |
| Thu, Apr 07 | Away vs Talawanda | W 13-5 | 5-1 |
| Fri, Apr 08 | Home vs Cancelled vs. Mt. Healthy | 5:00 PM | Event Cancelled |
| Sat, Apr 09 | Away vs Cancelled vs. Western Brown | 12:00 PM | Event Cancelled |
| Sat, Apr 09 | Away vs Cancelled vs. Little Miami | 2:00 PM | Event Cancelled |
| Mon, Apr 11 | Home vs Rescheduled vs. Northwest | 5:00 PM | Event Rescheduled |
| Tue, Apr 12 | Home vs Mercy McAuley | L 0-6 | 5-2 |
| Wed, Apr 13 | Away vs Ross | W 6-5 | 6-2 |
| Thu, Apr 14 | Home vs Northwest | W 13-0 | 7-2 |
| Fri, Apr 15 | Away vs Edgewood | W 15-0 | 8-2 |
| Sat, Apr 16 | Away vs Boone County | 12:00 PM | Boone County High School / Doubleheader Game 1 |
| Sat, Apr 16 | Away vs Boone County | 2:00 PM | Boone County High School / Doubleheader Game 2 |
| Wed, Apr 20 | Away vs Mt. Healthy | W 12-0 | 9-2 |
| Thu, Apr 21 | Home vs Talawanda | W 11-5 | 10-2 |
| Fri, Apr 22 | Away vs Northwest | W 16-2 | 11-2 |
| Mon, Apr 25 | Home vs Postponed vs. Ross | 5:00 PM | Event Postponed |
| Wed, Apr 27 | Home vs Edgewood | 5:00 PM | William Henry Harrison High School |
| Thu, Apr 28 | Home vs East Central | 5:00 PM | William Henry Harrison High School |
| Fri, Apr 29 | Away vs Talawanda | 5:00 PM | Talawanda High School |
| Mon, May 02 | Home vs Mt. Healthy | 5:00 PM | William Henry Harrison High School |
| Tue, May 03 | Home vs Cancelled vs. Taylor | 5:00 PM | Event Cancelled |
| Tue, May 03 | Home vs Postponed vs. Ross | 5:00 PM | Event Postponed |
| Wed, May 04 | Home vs Northwest | 5:00 PM | William Henry Harrison High School |
| Fri, May 06 | Away vs Postponed vs. Ross | 5:00 PM | Event Postponed |
| Mon, May 09 | Competes at Sectionals (H) vs Winton Woods | 5:00 PM | William Henry Harrison High School |
| Wed, May 11 | Competes at Sectionals (H) vs Kings | 5:00 PM | William Henry Harrison High School |
| Mon, May 16 | Away vs Ross | 5:00 PM | Ross High School |